Venkateswarlu, K.; Kelly, Steven L.; Kaderbhai, Naheed N.; Lamb, David C.; Kaderbhai, Mustak A.; Kelly, Diane E.
(2001-11-01)
Human sterol 14α-demethylase (P45051; CYP51) catalyzes the oxidative removal of the C32 methyl group of dihydrolanosterol, an essential step in the cholesterol biosynthetic pathway. The reaction is dependent upon NADPH ...