Browsing by Author "Beckmann, Manfred"

Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat

Tumilty, Les; Davison, Glen; Beckmann, Manfred; Thatcher, Rhys (2013)

Acute tyrosine administration is associated with increased exercise capacity in the heat. To explore whether reduced plasma tyrosine and phenylalanine (tyrosine precursor) is associated with impaired exercise capacity in ...

Data-driven strategy for the discovery of potential urinary biomarkers of habitual dietary exposure

Lloyd, Amanda Jane; Beckmann, Manfred; Haldar, Sumanto; Seal, Chris; Brandt, Kirsten; Draper, John (2013-02-01)

Background: An understanding of causal relations between diet and health is hindered by the lack of robust biological markers of food exposure. Objective: We aimed to develop a data-driven procedure to discover urine ...

Deciphering systemic wound responses of the pumpkin extrafascicular phloem by metabolomics and stable isotope-coded protein labeling (ICPL).

Graupels, Frank; Sarioglu, Hakan; Beckmann, Manfred; Hause, Bettina; Spannagl, Manuel; Draper, John; Lindermayr, Christian; Durner, Jörg (2012-12)

In cucurbits phloem latex exudes from cut sieve tubes of the extrafascicular phloem (EFP) serving in defense against herbivores. We analyzed inducible defense mechanisms in the EFP of Cucurbita maxima after leaf damage. ...

Detecting a difference - assessing generalisability when modelling metabolome fingerprint data in longer term studies of genetically modified plants

Enot, David P.; Beckmann, Manfred; Draper, John (2007-09)

There is current debate on whether genetically-manipulated plants might contain unexpected, potentially undesirable, changes in overall metabolite composition relative to that of the progenitor genotype. However, appropriate ...

Detection and Quantification of Tissue of Origin in Salmon and Veal Products using Methylation Sensitive AFLPs

Rodriguez Lopez, Carlos Marcelino; López, Rodríguez; Morán, Paloma; Lago, Fátima; Espiñeira, Montserrat; Beckmann, Manfred; Olmo, Sofia Consuegra Del (2012-04-15)

Food quality depends largely on the source of origin of the products used. Here we use methylation sensitive amplified polymorphisms (MSAP) analysis to diagnose and quantify the tissue of origin in salmon and veal products. ...

Detection and quantification of tissue of origin in salmon and veal products using methylation sensitive AFLPs

Rodriguez Lopez, Carlos Marcelino; Morán, Paloma; Lago, Fátima; Espiñeira, Montserrat; Beckmann, Manfred; Olmo, Sofia Consuegra Del (2012-04-15)

Food quality depends largely on the source of origin of the products used. Here we use methylation sensitive amplified polymorphisms (MSAP) analysis to diagnose and quantify the tissue of origin in salmon and veal products. ...

Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples

Favé, Gaëlle; Beckmann, Manfred; Lloyd, Amanda; Zhou, Shaobo; Harold, Graham; Lin, Wanchang; Tailliart, Kathleen; Xie, Long; Draper, John; Mathers, John C. (2011-12-01)

Conventional tools for measuring dietary exposure have well recognized limitations. Measurement of food-derived metabolites in biofluids provides an alternative approach and our aim was to develop an experimental protocol ...

Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: a review

Draper, John; Lloyd, Amanda Jane; Goodacre, Royston; Beckmann, Manfred (2013-03)

Producing a comprehensive overview of the chemical content of biologically-derived material is a major challenge. Apart from ensuring adequate metabolome coverage and issues of instrument dynamic range,mass resolution and ...

GC-MS Peak Labeling Under ArMet

Jenkins, Helen; Beckmann, Manfred; Draper, John; Hardy, Nigel (Springer, 2007)

Hierarchical metabolomics demonstrates substantial compositional similarity between genetically-modified and conventional potato crops

Catchpole, Gareth; Beckmann, Manfred; Enot, David P.; Mondhe, Madhav; Zywicki, Britta; Taylor, Janet; Hardy, Nigel; Smith, Aileen; King, Ross Donald; Kell, Douglas B.; Fiehn, Oliver; Draper, John (2005-10-04)

There is current debate whether genetically modified (GM) plants might contain unexpected, potentially undesirable changes in overall metabolite composition. However, appropriate analytical technology and acceptable metrics ...

Mass spectrometric monitoring of gases (CO2, CH4, O-2) in a mesotrophic peat core from Kopparas Mire, Sweden

Beckmann, Manfred; Lloyd, David (2001-02-01)

Membrane inlet mass spectrometry was used to monitor dissolved gas concentrations (CO2, CH4 and O2) in a mesotrophic peat core from Kopparås, Sweden. A comparison of depth profiles (down to 22 cm) with an ombrotrophic peat ...

Metabolic Engineering, metabolite profiling and machine learning to investigate the phloem-mobile signal in systemic acquired resistance in tobacco

Draper, John; Darby, Robert M.; Beckmann, Manfred; Maddison, A. L.; Mondhe, Madhav; Sheldrick, C.; Taylor, Janet; Goodacre, Royston; Kell, Douglas B. (2002)

The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato

Ward, Jane L.; Forcat, Silvia; Beckmann, Manfred; Bennett, Mark; Miller, Sonia J.; Baker, John M.; Hawkins, Nathaniel D.; Vermeer, Cornelia P.; Lu, Chuan; Lin, Wanchang; Truman, William M.; Beale, Michael H.; Draper, John; Mansfield, John W.; Grant, Murray (2010-05-18)

The outcome of bacterial infection of a plant is determined by the ability of the pathogen to successfully occupy the apoplastic space and deliver a constellation of effectors which collectively suppress basal and effector ...

The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato.

Ward, Jane L.; Forcat, Silvia; Beckmann, Manfred; Bennett, Mark; Miller, Sonia J.; Baker, John M.; Hawkins, Nathaniel D.; Vermeer, Cornelia P.; Lu, Chuan; Lin, Wanchang; Truman, William M.; Beale, Michael H.; Draper, John; Mansfield, John W.; Grant, Murray (2010-08)

The outcome of bacterial infection in plants is determined by the ability of the pathogen to successfully occupy the apoplastic space and deliver a constellation of effectors that collectively suppress basal and ...

Metabolomics and human nutrition

Primrose, Sandy; Draper, John; Elsom, Rachel; Kirkpatrick, Verity; Mathers, John C.; Seal, Chris; Beckmann, Manfred; Haldar, Sumanto; Beattie, John H.; Lodge, John K.; Jenab, Mazda; Keun, Hector; Scalbert, Augustin (2011-01-21)

The present report summarises a workshop convened by the UK Food Standards Agency (Agency) on 25 March 2010 to discuss the current Agency's funded research on the use of metabolomics technologies in human nutrition research. ...

On the interpretation of high throughput MS based metabolomics fingerprints with Random Forest

Enot, David P.; Beckmann, Manfred; Draper, John (Springer Berlin, 2006)

We discuss application of a machine learning method, Random Forest (RF), for the extraction of relevant biological knowledge from metabolomics fingerprinting experiments. The importance of RF margins and variable significance ...

Oral tyrosine supplementation improves exercise capacity in the heat

Tumilty, Les; Davison, Glen; Beckmann, Manfred; Thatcher, Rhys (2011-03-25)

Oral tyrosine supplementation improves exercise capacity in the heat

Tumilty, Les; Davison, Glen; Beckmann, Manfred; Thatcher, Rhys (1800)

Oral tyrosine supplementation improves exercise capacity in the heat

Tumilty, Les; Davison, Glen; Beckmann, Manfred; Thatcher, Rhys (2011-03-25)

Pheromonal communication in nereids and the likely intervention by petroleum derived pollutants

Muller, Carsten T.; Priesnitz, Frank M.; Beckmann, Manfred (2005-01)

Nereis succinea and Platynereis dumerilii (Annelida, Polychaeta) are broadcast spawners and reproduce semelparously. The final events in reproduction, swarming and spawning are co-ordinated by sex pheromones. A water-soluble ...

Browsing by Author "Beckmann, Manfred"

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Browsing by Author "Beckmann, Manfred"

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