Browsing by Author "Dunn, Warwick B."

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Browsing by Author "Dunn, Warwick B."

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  • Further developments towards a genome-scale metabolic model of yeast 
    Smallbone, Kieran; Kell, Douglas B.; Dunn, Warwick B.; Stanford, Natalie J.; Swainston, Neil; Fisher, Paul; Jameson, Daniel; Simeonidis, Evangelos; Dobson, Paul D.; Hull, Duncan; Lu, Chuan; Oliver, Stephen G.; Lanthaler, Karin; King, Ross Donald; Mendes, Pedro; Oshota, Olusegun; Pir, Pınar; Brown, Marie; Stevens, Robert D. (2011-06-06)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...
  • Measuring the metabolome: current analytical technologies 
    Dunn, Warwick B.; Johnson, Helen E.; Bailey, N. J. C. (2005-03-04)
    The post-genomics era has brought with it ever increasing demands to observe and characterise variation within biological systems. This variation has been studied at the genomic (gene function), proteomic (protein regulation) ...
  • Metabolic footprinting and systems biology: the medium is the message. 
    Kell, Douglas B.; Brown, Marie; Davey, Hazel M.; Dunn, Warwick B.; Spasić, Irena; Oliver, Stephen G. (2005-07)
    One element of classical systems analysis treats a system as a black or grey box, the inner structure and behaviour of which can be analysed and modelled by varying an internal or external condition, probing it from outside ...
  • Metabolomic approaches indicate that cell wall modifications play a major role in ethylene-mediated resistance against Botrytis cinerea 
    Lloyd, A. J.; Allwood, J. William; Winder, Catherine L.; Dunn, Warwick B.; Heald, J. K.; Cristescu, Simona M.; Sivakumaran, A.; Harren, Frans J. M.; Mulema, Joseph; Denby, Katherine; Goodacre, Royston; Smith, A. R.; Mur, L. A. J. (2011-09)
    In Arabidopsis, resistance to the necrotrophic fungus Botrytis cinerea is conferred by ethylene via poorly understood mechanisms. Metabolomic approaches compared the responses of the wild-type, the ethylene-insensitive ...