Browsing by Author "Fiehn, Oliver"

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  • Taylor, Janet; King, Ross Donald; Altmann, Thomas; Fiehn, Oliver (2002)
    MOTIVATION: Metabolomics is a post genomic technology which seeks to provide a comprehensive profile of all the metabolites present in a biological sample. This complements the mRNA profiles provided by microarrays, and ...
  • Zywicki, Britta; Catchpole, Gareth; Fiehn, Oliver; Draper, John H. (2005)
    Two rapid methods for highly selective detection and quantification of the two major glycoalkaloids in potatoes, α-chaconine and α-solanine, were compared for robustness in high-throughput operations for over 1000 analytical ...
  • Fiehn, Oliver; Kristal, Bruce; Ommen, Ben van; Sumner, Lloyd W.; Sansone, Susanna-Assunta; Taylor, Chris F.; Hardy, Nigel; Kaddurah-Daouk, Rima (2006-06)
    Metabolite concentrations in cellular systems are very much dependent on the physiological, environmental, and genetic status of an organism and are regarded as the ultimate result of cellular regulation, resulting in the ...
  • Kristal, Bruce; Fiehn, Oliver; Kaddurah-Daouk, Rima; Sumner, Lloyd W.; Taylor, Chris F.; Hardy, Nigel; Ommen, Ben van; Sansone, Susanna-Assunta (2006-08-24)
    Metabolite concentrations in cellular systems are very much dependent on the physiological, environmental, and genetic status of an organism and are regarded as the ultimate result of cellular regulation, resulting in the ...
  • Catchpole, Gareth; Beckmann, Manfred; Enot, David Pierre Louis; Mondhe, Madhav; Zywicki, Britta; Taylor, Janet; Hardy, Nigel William; Smith, Aileen Roberta; King, Ross Donald; Kell, Douglas B.; Fiehn, Oliver; Draper, John (2005-10-04)
    There is current debate whether genetically modified (GM) plants might contain unexpected, potentially undesirable changes in overall metabolite composition. However, appropriate analytical technology and acceptable metrics ...
  • Fiehn, Oliver; Robertson, Donald; Griffin, Julian L.; van der Werf, Mariet; Nikolau, Basil; Morrison, Norman; Sumner, Lloyd W.; Goodacre, Royston; Hardy, Nigel; Taylor, Chris F.; Fostel, Jennifer; Kristal, Bruce; Kaddurah-Daouk, Rima; Mendes, Pedro; van Ommen, B.; Lindon, John C.; Sansone, Susanna-Assunta (2007-09-01)
    In 2005, the Metabolomics Standards Initiative has been formed. An outline and general introduction is provided to inform about the history, structure, working plan and intentions of this initiative. Comments on any of the ...
  • Kristal, Bruce; Nikolau, Basil; Mendes, Pedro; Goodacre, Royston; Hardy, Nigel; Griffin, Julian L.; Fiehn, Oliver; Morrison, N.; Kaddurah-Daouk, Rima; Sumner, Lloyd W.; van der Werf, M.; Fostel, Jennifer; Taylor, Chris F.; Lindon, John C.; Sansone, Susanna-Assunta; van Ommen, B.; Robertson, Donald (2007-12-05)
    In 2005, the Metabolomics Standards Initiative has been formed. An outline and general introduction is provided to inform about the history, structure, working plan and intentions of this initiative. Comments on any of the ...
  • Hall, Robert D.; Beale, Michael H.; Fiehn, Oliver; Hardy, Nigel; Sumner, Lloyd W.; Bino, Raoul J. (2002-07)
    After the establishment of technologies for high-throughput DNA sequencing (genomics), gene expression analysis (transcriptomics), and protein analysis (proteomics), the remaining functional genomics challenge is that of ...
  • Bino, Raoul J.; Sumner, Lloyd W.; Beale, Michael H.; Hall, Robert D.; Hardy, Nigel; Fiehn, Oliver (2006-03-16)
  • Bino, Raoul J.; Hall, Robert D.; Fiehn, Oliver; Kopka, Joachim; Saito, Kazuki; Draper, John H.; Nikolau, Basil J.; Mendes, Pedro; Roessner-Tunali, Ute; Beale, Michael H.; Trethewey, Richard N.; Lange, B. Markus; Wurtele, Eve Syrkin; Sumner, Lloyd W. (2004-09)
    Metabolomics is developing as an important functional genomics tool; however, there is still room for technical improvements in both the large-scale determination of metabolites from complex plant tissues and the dissemination ...
  • Taylor, Chris F.; Field, Dawn; Sansone, Susanna-Assunta; Aerts, Jan; Apweiler, Rolf; Ashburner, Michael; Ball, Catherine A.; Binz, Pierre-Alain; Bogue, Molly; Booth, Tim; Brazma, Alvis; Brinkman, Ryan R.; Michael Clark, Adam; Deutsch, Eric W.; Fiehn, Oliver; Fostel, Jennifer; Ghazal, Peter; Gibson, Frank; Gray, Tanya; Grimes, Graeme; Hancock, John M.; Hardy, Nigel W.; Hermjakob, Henning; Julian, Jr., Randall K.; Kane, Matthew; Kettner, Carsten; Kinsinger, Christopher; Kolker, Eugene; Kuiper, Martin; Novère, Nicolas Le; Leebens-Mack, Jim; Lewis, Suzanna E.; Lord, Phillip; Mallon, Ann-Marie; Marthandan, Nishanth; Masuya, Hiroshi; McNally, Ruth; Mehrle, Alexander; Morrison, Norman; Orchard, Sandra; Quackenbush, John; Reecy, James M.; Robertson, Donald G.; Rocca-Serra, Philippe; Rodriguez, Henry; Rosenfelder, Heiko; Santoyo-Lopez, Javier; Scheuermann, Richard H.; Schober, Daniel; Smith, Barry; Snape, Jason; Stoeckert, Jr., Christian J.; Tipton, Keith; Sterk, Peter; Untergasser, Andreas; Vandesompele, Jo; Wiemann, Stefan (2008-08-01)
    The Minimum Information for Biological and Biomedical Investigations (MIBBI) project provides a resource for those exploring the range of extant minimum information checklists and fosters coordinated development of such ...
  • Sterk, Peter; Leebens-Mack, Jim; Brinkman, Ryan R.; Lord, Phillip; Kane, Matthew; Quackenbush, John; McNally, Ruth; Scheuermann, Richard H.; Le Novère, Nicolas; Mallon, Ann-Marie; Smith, Barry; Rocca-Serra, Philippe; Field, Dawn; Deutsch, Eric W.; Kinsinger, Christopher; Vandesompele, Jo; Lewis, Suzanna E.; Stoeckert, Christian J. Jr; Brazma, Alvis; Untergasser, Andreas; Reecy, James M.; Rodriguez, Henry; Morrison, Norman; Ball, Catherine A.; Ghazal, Peter; Rosenfelder, Heiko; Clark, Adam Michael; Gray, Tanya; Fiehn, Oliver; Mehrle, Alexander; Kuiper, Martin; Apweiler, Rolf; Kettner, Carsten; Masuya, Hiroshi; Snape, Jason; Ashburner, Michael; Bogue, Molly; Hermjakob, Henning; Julian, Randall K. Jr; Sansone, Susanna-Assunta; Aerts, Jan; Grimes, Graeme; Hardy, Nigel; Marthandan, Nishanth; Wiemann, Stefan; Binz, Pierre-Alain; Gibson, Frank; Kolker, Eugene; Orchard, Sandra; Schober, Daniel; Booth, Tim; Taylor, Chris F.; Fostel, Jennifer; Tipton, Keith; Robertson, Donald G.; Santoyo-Lopez, Javier; Hancock, John M. (2012-04-23)
    The Minimum Information for Biological and Biomedical Investigations (MIBBI) project provides a resource for those exploring the range of extant minimum information checklists and fosters coordinated development of such ...
  • Jenkins, Helen Ann; Hardy, Nigel William; Beckmann, Manfred; Draper, John; Smith, Aileen Roberta; Taylor, Janet; Fiehn, Oliver; Goodacre, Royston; Bino, Raoul J.; Hall, Robert D.; Kopka, Joachim; Lane, Geoffrey A; Lange, Markus; Liu, Jang R; Mendes, Pedro; Nikolau, Basil J; Oliver, Stephen G.; Paton, Norman W.; Rhee, Sue; Roessner-Tunali, Ute; Saito, Kazuki; Smedsgaard, Jørn; Sumner, Lloyd W.; Wang, Trevor; Walsh, Sean; Wurtele, Eve Syrkin; Kell, Douglas B. (2004-12-06)
    The study of the metabolite complement of biological samples, known as metabolomics, is creating large amounts of data, and support for handling these data sets is required to facilitate meaningful analyses that will answer ...
  • Sumner, Lloyd W.; Amberg, Alexander; Barrett, Dave; Beale, Michael H.; Beger, Richard; Daykin, Clare; Fan, Teresa; Fiehn, Oliver; Goodacre, Royston; Griffin, Julian L.; Hankemeier, Thomas; Hardy, Nigel; Harnly, James; Higashi, Richard; Kopka, Joachim; Lane, Andrew N.; Lindon, John C.; Marriott, Philip; Nicholls, Andrew W.; Reily, Michael D.; Thaden, John J.; Viant, Mark R. (2007-09-01)
    There is a general consensus that supports the need for standardized reporting of metadata or information describing large-scale metabolomics and other functional genomics data sets. Reporting of standard metadata provides ...
  • Kopka, Joachim; Beale, Michael H.; Fan, T.; Daykin, Clare; Fiehn, Oliver; Goodacre, Royston; Higashi, R.; Reily, Michael; Harnly, J.; Amberg, Alexander; Hankemeier, T.; Barrett, D.; Griffin, Julian L.; Hardy, Nigel; Thaden, J.; Beger, Richard; Sumner, Lloyd W.; Viant, Mark R.; Nicholls, A.; Marriott, P.; Lindon, John C.; Lane, A. (2007-12-05)
    There is a general consensus that supports the need for standardized reporting of metadata or information describing large-scale metabolomics and other functional genomics data sets. Reporting of standard metadata provides ...