Browsing by Author "Horne, Graeme"

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Browsing by Author "Horne, Graeme"

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  • Isolation synthesis and glycosidase inhibition profile of 3-epi-casuarine 
    Nash, Robert J.; Evinson, Emma L.; Horne, Graeme; Fleet, George W. J.; Dwek, R. A.; Ameijde, Jeroen V.; Jones, Paul W.; Wormald, M. R. (2006-10-31)
    3-epi-Casuarine, the first naturally occurring stereoisomer of casuarine, was isolated from Myrtus communis L. The glycosidase inhibition profile and NMR spectra of 3-epi-casuarine are compared with those of casuarine; the ...
  • Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization 
    Sato, Kasumi; Yu, Chi-Yi; Zhang, Wei; van Well, Renate; Horne, Graeme; Jia, Yue-Mei; Fleet, George W. J.; Wilson, Francis X.; Kato, Atsushi; Nash, Robert J.; Hu, Xiang-Guo (2011-10-31)
    Total synthesis of the proposed structure of (-)-hyacinthacine C(5) and its epimers at C6 and C7 is described. A key step of the synthesis was the construction of the bicyclic pyrrolizidine system by means of a nucleophilic ...