Browsing by Author "Mendes, Pedro"

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Browsing by Author "Mendes, Pedro"

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  • Constraint-based optimisation tools for semi-automated refinement of genome-scale yeast metabolic models 
    Pir, Pinar; Dobson, Paul D.; Smallbone, Kieran; Mendes, Pedro; King, Ross Donald; Lu, Chuan; Oliver, Stephen G.; Clare, Amanda (2010-10)
    Background: Genome-scale metabolic network models have been widely used for analysing the cellular behaviour of organisms both qualitatively and quantitatively. An iterative semi-automated procedure for model validation ...
  • Further developments towards a genome-scale metabolic model of yeast 
    Smallbone, Kieran; Kell, Douglas B.; Dunn, Warwick B.; Stanford, Natalie J.; Swainston, Neil; Fisher, Paul; Jameson, Daniel; Simeonidis, Evangelos; Dobson, Paul D.; Hull, Duncan; Lu, Chuan; Oliver, Stephen G.; Lanthaler, Karin; King, Ross Donald; Mendes, Pedro; Oshota, Olusegun; Pir, Pınar; Brown, Marie; Stevens, Robert D. (2011-06-06)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...
  • MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems 
    Mendes, Pedro; Kell, Douglas B. (2001)
    Summary: We describe a program for the construction of spatially distributed metabolic models, which may then be simulated using the metabolic simulator Gepasi. This is useful for the modelling of heterogeneous systems ...
  • A proposed framework for the description of plant metabolomics experiments and their results 
    Jenkins, Helen; Hardy, Nigel; Beckmann, Manfred; Draper, John; Smith, Aileen R.; Taylor, Janet; Fiehn, Oliver; Goodacre, Royston; Bino, Raoul J.; Hall, Robert D.; Kopka, Joachim; Lane, Geoffrey A; Lange, Markus; Liu, Jang R; Mendes, Pedro; Nikolau, Basil J; Oliver, Stephen G.; Paton, Norman W.; Rhee, Sue; Roessner-Tunali, Ute; Saito, Kazuki; Smedsgaard, Jørn; Sumner, Lloyd W.; Wang, Trevor; Walsh, Sean; Wurtele, Eve Syrkin; Kell, Douglas B. (2004-12-06)
    The study of the metabolite complement of biological samples, known as metabolomics, is creating large amounts of data, and support for handling these data sets is required to facilitate meaningful analyses that will answer ...