Adachi, Isao; Nash, Robert J.; Kobayashi, Kaori; Kato, Atsushi; Hirono, Shuichi; Narukawa, Kayo; Minoshima, Yuka
(2010-08-12)
We report the structure–activity relationship of a series of coumarins as aldose reductase 2 (ALR2) inhibitors and their suppressive effect on the accumulation of galactitol in the rat lens. We evaluated their ALR2 selectivity ...