Browsing by Author "O'Neill, Sandra M."

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  • Hamilton, Clare M.; Dowling, David J.; Loscher, Christine E.; Morphew, Russell M.; Brophy, Peter M.; O'Neill, Sandra M. (2009-06-01)
    Parasitic worms and molecules derived from them have powerful anti-inflammatory properties and are shown to have therapeutic effects on inflammatory diseases. The helminth Fasciola hepatica has been reported to suppress ...
  • Morphew, R. M.; Hamilton, Clare M.; Wright, H. A.; Dowling, David J.; O'Neill, Sandra M.; Brophy, P. M. (2013-01-31)
    Fasciola hepatica NP-40 released protein extract (FhNPE) exhibits potent Th1 immunosuppressive properties in vitro and in vivo. However, the protein composition of this active fraction, responsible for Th1 immune modulatory ...
  • LaCourse, E. James; Perally, S.; Morphew, R. M.; Moxon, J. V.; Prescott, Mark C.; Dowling, David J.; O'Neill, Sandra M.; Kipar, Anja; Hetzel, Udo; Hoey, Elizabeth; Zafra, Rafael; Buffoni, Leandro; Arévalo, José Pérez; Brophy, P. M. (2012-05-01)
    Background: Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no ...