Browsing by Author "Takakura, Ikuro"

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  • Miyazawa, Kohtaro; Hondo, Tetsuya; Kanaya, Takashi; Tanaka, Sachi; Takakura, Ikuro; Itani, Wataru; Rose, Michael Terence; Kitazawa, Haruki; Yamaguchi, Takahiro; Aso, Hisashi (2010-01)
    Membranous epithelial cells (M cells) of the follicle-associated epithelium in Peyer's patches have a high capacity for transcytosis of several viruses and microorganisms. Here, we report that we have successfully established ...
  • Rose, Michael T.; Itani, Wataru; Miyazawa, K.; Yamaguchi, Takahiro; Takakura, Ikuro; Tanaka, Sachi; Kanaya, T.; Aso, Hisashi (2011-06-09)
    Membranous epithelial cells (M cells) of the follicle-associated epithelium in Peyer¿s patches have a high capacity for transcytosis of several viruses and microorganisms. Here, we report that we have successfully established ...
  • Hondo, Tetsuya; Kanaya, Takashi; Takakura, Ikuro; Watanabe, Hitoshi; Takahashi, Yu; Nagasawa, Yuya; Terada, Shunsuke; Ohwada, Shyuichi; Watanabe, Kouichi; Kitazawa, Haruki; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2011-03-01)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Kanaya, Takashi; Miyazawa, Kohtaro; Takakura, Ikuro; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, M. T.; McConochie, H. R.; Okano, Hideyuki; Yamaguchi, Takahiro; Aso, Hisashi (2008-08-01)
    M cells are a kind of intestinal epithelial cell in the follicle-associated epithelium of Peyer's patches. These cells can transport antigens and microorganisms into underlying lymphoid tissues. Despite the important role ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Tanaka, Sachi; Takakura, Ikuro; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T.; Sakaguchi, Suehiro; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2007-03)
    The gastrointestinal tract is thought to be the main site of entry for the pathological isoform of the prion protein (PrPSc). Prion diseases are believed to result from a conformational change of the cellular prion protein ...
  • Takakura, Ikuro; Miyazawa, Kohtaro; Kanaya, Takashi; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Watanabe, Hitoshi; Hondo, Tetsuya; Rose, Michael T; Mori, Tsuyoshi; Sakaguchi, Suehiro; Nishida, Noriyuki; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2011-09)
    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice, ...
  • Watanabe, Hitoshi; Akasaka, Daisuke; Ogasawara, Hideki; Sato, Kan; Miyake, Masato; Saito, Kazuki; Takahashi, Yu; Kanaya, Takashi; Takakura, Ikuro; Hondo, Tetsuya; Chao, Guozheng; Rose, Michael Terence; Ohwada, Shyuichi; Watanabe, Kouichi; Yamaguchi, Takahiro; Aso, Hisashi (2010-10-01)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Hondo, Tetsuya; Takahashi, Yu; Kanaya, T.; Sato, Kan; Ogasawara, Hideki; Miyake, Masato; Saito, Kazuki; Takakura, Ikuro; al, et; Akasaka, Daisuke; Watanabe, Hitoshi (2011-06-03)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Takakura, Ikuro; Tanaka, Sachi; Hondo, Tetsuya; Watanabe, Hitoshi; Rose, Michael Terence; Kitazawa, Haruki; Yamaguchi, Takahiro; Katamine, Shigeru; Nishida, Noriyuki; Aso, Hisashi (2010-12)
    Transmissible spongiform encephalopathies (TSE), including bovine spongiform encephalopathy (BSE), are fatal neurodegenerative disorders in humans and animals. BSE appears to have spread to cattle through the consumption ...
  • Yamaguchi, Takahiro; Rose, Michael T.; Miyazawa, K.; Tanaka, Sachi; Watanabe, Hitoshi; Kanaya, T.; Takakura, Ikuro; al, et; Katamine, Shigeru; Kitazawa, Haruki; Hondo, Tetsuya (2011-06-06)
    Transmissible spongiform encephalopathies (TSE), including bovine spongiform encephalopathy (BSE), are fatal neurodegenerative disorders in humans and animals. BSE appears to have spread to cattle through the consumption ...