Browsing by Author "Watanabe, Hitoshi"

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  • Hondo, Tetsuya; Someya, Shunsuke; Nagasawa, Yuya; Terada, Shunsuke; Watanabe, Hitoshi; Chen, Xiangning; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael; Nochi, Tomonori; Aso, Hisashi (2016-02-22)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer’s patches contribute to the mucosal immune response by the transcytosis of microorganisms. The mechanism by which M cells take up microorganisms, and ...
  • Hondo, Tetsuya; Kanaya, Takashi; Takakura, Ikuro; Watanabe, Hitoshi; Takahashi, Yu; Nagasawa, Yuya; Terada, Shunsuke; Ohwada, Shyuichi; Watanabe, Kouichi; Kitazawa, Haruki; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2011-03-01)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Yamaguchi, T.; Ohwada, S.; Hondo, Tetsuya; Takahashi, Y.; Kitazawa, Haruki; Nagasawa, Y.; Watanabe, K.; Takakura, I.; Rose, Michael; Terada, S.; Kanaya, T.; Watanabe, Hitoshi; Aso, Hisashi (2011-05-16)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Hondo, Tetsuya; Kanaya, Takashi; Takakura, Ikuro; Watanabe, Hitoshi; Takahashi, Yu; Nagasawa, Yuya; Terada, Shunsuke; Ohwada, Shyuichi; Watanabe, Kouichi; Kitazawa, Haruki; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2011-03-01)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Watanabe, Hitoshi; Saito, Ryo; Nakano, Tatsuya; Takahashi, Hideyuki; Takahashi, Yu; Sumiyoshi, Keisuke; Sato, Katsuyoshi; Chen, Xiangning; Okada, Natsumi; Iwasaki, Shunsuke; Harjanti, Dian W.; Sekiguchi, Natsumi; Sano, Hiroaki; Kitazawa, Haruki; Rose, Michael T.; Ohwada, Shyuichi; Watanabe, Kouichi; Aso, Hisashi (2014-02-04)
    In mice, peripheral 5-HT induces an increase in the plasma concentrations of glucose, insulin and bile acids, and a decrease in plasma triglyceride, NEFA and cholesterol concentrations. However, given the unique characteristics ...
  • Iwasaki, Shunsuke; Miyake, Masato; Watanabe, Hitoshi; Kitagawa, Eri; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael Terence; Aso, Hisashi (2013-02)
    Recent studies show that myostatin mRNA expression is found in some regions of the brain. However, the functional significance of this is currently unknown. We therefore investigated myostatin expression and function in ...
  • Iwasaki, Shunsuke; Miyake, Masato; Watanabe, Hitoshi; Kitagawa, Eri; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael Terence; Aso, Hisashi (2013-02)
    Recent studies show that myostatin mRNA expression is found in some regions of the brain. However, the functional significance of this is currently unknown. We therefore investigated myostatin expression and function in ...
  • Takakura, Ikuro; Miyazawa, Kohtaro; Kanaya, Takashi; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Watanabe, Hitoshi; Hondo, Tetsuya; Rose, Michael T; Mori, Tsuyoshi; Sakaguchi, Suehiro; Nishida, Noriyuki; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2011-09)
    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice, ...
  • Takakura, Ikuro; Miyazawa, Kohtaro; Kanaya, Takashi; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Watanabe, Hitoshi; Hondo, Tetsuya; Rose, Michael T; Mori, Tsuyoshi; Sakaguchi, Suehiro; Nishida, Noriyuki; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2011-09)
    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice, ...
  • Watanabe, Hitoshi; Akasaka, Daisuke; Ogasawara, Hideki; Sato, Kan; Miyake, Masato; Saito, Kazuki; Takahashi, Yu; Kanaya, Takashi; Takakura, Ikuro; Hondo, Tetsuya; Chao, Guozheng; Rose, Michael Terence; Ohwada, Shyuichi; Watanabe, Kouichi; Yamaguchi, Takahiro; Aso, Hisashi (2010-10-01)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Hondo, Tetsuya; Takahashi, Yu; Kanaya, T.; Sato, Kan; Ogasawara, Hideki; Miyake, Masato; Saito, Kazuki; Takakura, Ikuro; al, et; Akasaka, Daisuke; Watanabe, Hitoshi (2011-06-03)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Watanabe, Hitoshi; Akasaka, Daisuke; Ogasawara, Hideki; Sato, Kan; Miyake, Masato; Saito, Kazuki; Takahashi, Yu; Kanaya, Takashi; Takakura, Ikuro; Hondo, Tetsuya; Chao, Guozheng; Rose, Michael Terence; Ohwada, Shyuichi; Watanabe, Kouichi; Yamaguchi, Takahiro; Aso, Hisashi (2010-10-01)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Watanabe, Hitoshi; Rose, Michael Terence; Aso, Hisashi (2011-06-01)
    Purpose of review: Two independent serotonin systems exist, one in the brain and the other in the periphery. Serotonin is a well known monoaminergic neurotransmitter in the central nervous system and it is known to regulate ...
  • Watanabe, Hitoshi; Nakano, Tatsuya; Saito, Ryo; Aksaka, D; Saito, K; Ogasawara, Hideki; Minashima, Takeshi; Miyazawa, Kohtaro; Kanaya, Takashi; Takakura, Ikuro; Inoue, N; Ikeda, Ikuo; Chen, X; Miyake, M.; kitazawa, haruki; Shirakawa, H; Sato, Katsuyoshi; Tahara, Koji; Nagasawa, Yuya; Watanabe, Kouichi; Rose, Michael; Aso, Hisashi (2016-01-14)
    There are two independent serotonin (5-HT) systems of organization: one in the central nervous system and the other in the periphery. 5-HT affects feeding behavior and obesity in the central nervous system. On the other ...
  • Watanabe, Hitoshi; Chen, Xiangning; Shoji, Noriaki; Saito, Ryo; Nakano, Tatsuya; Saito, Kazuki; Sumiyoshi, Keisuke; Rose, Michael; Okada, Natumi; Watanabe, Kouichi; Aso, Hisashi (2015-07)
    It is desirable to produce beef with high levels of monounsaturated fatty acids (MUFA), as this is related to fat softness and palatability. However, the physiology of MUFA synthesis in bovine fat during the fattening ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Takakura, Ikuro; Tanaka, Sachi; Hondo, Tetsuya; Watanabe, Hitoshi; Rose, Michael Terence; Kitazawa, Haruki; Yamaguchi, Takahiro; Katamine, Shigeru; Nishida, Noriyuki; Aso, Hisashi (2010-12)
    Transmissible spongiform encephalopathies (TSE), including bovine spongiform encephalopathy (BSE), are fatal neurodegenerative disorders in humans and animals. BSE appears to have spread to cattle through the consumption ...
  • Yamaguchi, Takahiro; Rose, Michael T.; Miyazawa, K.; Tanaka, Sachi; Watanabe, Hitoshi; Kanaya, T.; Takakura, Ikuro; al, et; Katamine, Shigeru; Kitazawa, Haruki; Hondo, Tetsuya (2011-06-06)
    Transmissible spongiform encephalopathies (TSE), including bovine spongiform encephalopathy (BSE), are fatal neurodegenerative disorders in humans and animals. BSE appears to have spread to cattle through the consumption ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Takakura, Ikuro; Tanaka, Sachi; Hondo, Tetsuya; Watanabe, Hitoshi; Rose, Michael Terence; Kitazawa, Haruki; Yamaguchi, Takahiro; Katamine, Shigeru; Nishida, Noriyuki; Aso, Hisashi (2010-12)
    Transmissible spongiform encephalopathies (TSE), including bovine spongiform encephalopathy (BSE), are fatal neurodegenerative disorders in humans and animals. BSE appears to have spread to cattle through the consumption ...