Browsing by Author "Watanabe, Kouichi"

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  • Nagai, Yasuhiro; Aso, Hisashi; Ogasawara, Hidiki; Tanaka, Sachi; Taketa, Yoshikazu; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, M. T.; Kitazawa, Haruki; Yamaguchi, Takahiro (2008-11-01)
    Stem/Progenitor cells in the postnatal pituitary gland are embedded in a marginal cell layer around Rathke’s pouch. However, the nature and behavior of anterior pituitary progenitor cells remain unclear. We established ...
  • Nagai, Yasuhiro; Aso, Hisashi; Ogasawara, Hideki; Tanaka, Sachi; Taketa, Yoshikazu; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, Michael T.; Kitazawa, Haruki; Yamaguchi, Takahiro (2008-11-01)
    Stem/Progenitor cells in the postnatal pituitary gland are embedded in a marginal cell layer around Rathke’s pouch. However, the nature and behavior of anterior pituitary progenitor cells remain unclear. We established ...
  • Miyazawa, Kohtaro; Aso, Hisashi; Kanaya, Takashi; Kido, Taketomo; Minashima, Takeshi; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T.; Tahara, Koji; Yamasaki, Tadashi; Yamaguchi, Takahiro (2006-03)
    Membranous (M) cells of the follicle-associated epithelium (FAE) are believed to sample antigens from the gut lumen. However, the origin, differentiation mechanism, and cell death of M cells are still a matter of controversy. ...
  • Sanosaka, Masato; Minashima, Takeshi; Suzuki, Keiichi; Watanabe, Kouichi; Ohwada, Shyuichi; Hagino, Akihiko; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2008-02)
    To understand the relationship between intramuscular adipogenesis in the pig and the supply fatty acids, we established a clonal porcine intramuscular preadipocyte (PIP) line from the marbling muscle tissue of female Duroc ...
  • Hondo, Tetsuya; Kanaya, Takashi; Takakura, Ikuro; Watanabe, Hitoshi; Takahashi, Yu; Nagasawa, Yuya; Terada, Shunsuke; Ohwada, Shyuichi; Watanabe, Kouichi; Kitazawa, Haruki; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2011-03-01)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Kanaya, Takashi; Miyazawa, Kohtaro; Takakura, Ikuro; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, M. T.; McConochie, H. R.; Okano, Hideyuki; Yamaguchi, Takahiro; Aso, Hisashi (2008-08-01)
    M cells are a kind of intestinal epithelial cell in the follicle-associated epithelium of Peyer's patches. These cells can transport antigens and microorganisms into underlying lymphoid tissues. Despite the important role ...
  • Iwasaki, Shunsuke; Miyake, Masato; Watanabe, Hitoshi; Kitagawa, Eri; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael Terence; Aso, Hisashi (2013-02)
    Recent studies show that myostatin mRNA expression is found in some regions of the brain. However, the functional significance of this is currently unknown. We therefore investigated myostatin expression and function in ...
  • Miyazawa, Kohtaro; Aso, Hisashi; Honda, Masashi; Kido, Taketomo; Minashima, Takeshi; Kanaya, Takashi; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, Michael T.; Yamaguchi, Takahiro (2006-08)
    Dendritic cells (DCs) are professional antigen presenting cells, which initiate primary immune responses and also play an important role in the generation of peripheral tolerance. There is no reliable method established ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Tanaka, Sachi; Takakura, Ikuro; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T.; Sakaguchi, Suehiro; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2007-03)
    The gastrointestinal tract is thought to be the main site of entry for the pathological isoform of the prion protein (PrPSc). Prion diseases are believed to result from a conformational change of the cellular prion protein ...
  • Takakura, Ikuro; Miyazawa, Kohtaro; Kanaya, Takashi; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Watanabe, Hitoshi; Hondo, Tetsuya; Rose, Michael T; Mori, Tsuyoshi; Sakaguchi, Suehiro; Nishida, Noriyuki; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2011-09)
    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice, ...
  • Watanabe, Hitoshi; Akasaka, Daisuke; Ogasawara, Hideki; Sato, Kan; Miyake, Masato; Saito, Kazuki; Takahashi, Yu; Kanaya, Takashi; Takakura, Ikuro; Hondo, Tetsuya; Chao, Guozheng; Rose, Michael Terence; Ohwada, Shyuichi; Watanabe, Kouichi; Yamaguchi, Takahiro; Aso, Hisashi (2010-10-01)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Kanaya, Takashi; Aso, Hisashi; Miyazawa, Kohtaro; Kido, Taketomo; Minashima, Takeshi; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T; Yamaguchi, Takahiro (2007-04)
    M cells play a central role in the initiation of mucosal immune responses. However, a primary source of difficulty for investigations of this is the lack of an available specific marker for bovine M cells. As M cells possess ...