Background: The inference of homology between proteins is a key problem in molecular biology The current best approaches only identify ~50% of homologies (with a false positive rate set at 1/ 1000). Results: We present ...

We wished to quantify the state-of-the-art of our understanding of clusters in microarray data. To do this we systematically compared the clusters produced on sets of microarray data using a representative set of clustering ...

Phenotype ontologies are typically constructed to serve the needs of a particular community, such as annotation of genotype-phenotype associations in mouse or human. Here we demonstrate how these ontologies can be improved ...

The automation of laboratory techniques has greatly increased the number of experiments that can be carried out in the chemical and biological sciences. Until recently, this automation has focused primarily on improving ...

Logical Information Systems (LIS) use logic in a uniform way to describe their contents, to query it, to navigate through it, to analyze it, and to maintain it. They can be given an abstract speci¯cation that does not ...

Background: We are interested in understanding the locational distribution of genes and their functions in genomes, as this distribution has both functional and evolutionary significance. Gene locational distribution is ...

OBJECTIVE: To assess the impact of the introduction of an ultrasound-based model of care for women with acute gynecological complications. METHODS: This was a prospective comparative study of women attending an ultrasound-based ...

The diffusion and transfer of knowledge is central to the process of innovation and is of importance to both academics and industrialists. In this paper, we propose that academic articles and patent documents referring to ...