Browsing Bioinformatics and Computational Biology Group by Author "Kell, Douglas B."


Browsing Bioinformatics and Computational Biology Group by Author "Kell, Douglas B."

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  • Woodward, Andrew M.; Rowland, Jem; Kell, Douglas B. (2004)
    Image registration describes the process of manipulating a distorted version of an image such that its pixels overlay the equivalent pixels in a clean, master or reference image. The need for it has assumed particular ...
  • King, Ross Donald; Whelan, Kenneth Edward; Jones, Ffion M.; Reiser, Philip G. K.; Bryant, Christopher H.; Muggleton, Stephen H.; Kell, Douglas B.; Oliver, Stephen G. (2004-01-15)
    The question of whether it is possible to automate the scientific process is of both great theoretical interest and increasing practical importance because, in many scientific areas, data are being generated much faster ...
  • Dobson, Paul D.; Smallbone, Kieran; Jameson, Daniel; Simeonidis, Evangelos; Lanthaler, Karin; Pir, Pınar; Lu, Chuan; Swainston, Neil; Dunn, Warwick B.; Fisher, Paul; Hull, Duncan; Brown, Marie; Oshota, Olusegun; Stanford, Natalie J.; Kell, Douglas B.; King, Ross Donald; Oliver, Stephen G.; Stevens, Robert D.; Mendes, Pedro (2010-10-28)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...
  • Pritchard, Leighton; Corne, D.; Kell, Douglas B.; Winson, Mike K.; Rowland, Jeremy John (2005-06-21)
    In this paper, we generalise a previously-described model of the error-prone polymerase chain reaction (PCR) reaction to conditions of arbitrarily variable amplification efficiency and initial population size. Generalisation ...
  • Spasić, Irena; Dunn, Warwick B.; Velarde, Giles; Tseng, Andy; Jenkins, Helen; Hardy, Nigel; Oliver, Stephen G.; Kell, Douglas B. (2006-06-05)
    Background The genome sequencing projects have shown our limited knowledge regarding gene function, e.g. S. cerevisiae has 5–6,000 genes of which nearly 1,000 have an uncertain function. Their gross influence on the behaviour ...
  • Hesketh, A. R.; Chandra, G.; Shaw, Adrian; Rowland, Jem; Kell, Douglas B.; Bibb, M. J.; Chater, K. F. (2002)
    The newly sequenced genome of Streptomyces coelicolor is estimated to encode 7825 theoretical proteins. We have mapped approximately 10% of the theoretical proteome experimentally using two-dimensional gel electrophoresis ...

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