Browsing Computational Biology and Bioinformatics by Author "Kell, Douglas B."

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Browsing Computational Biology and Bioinformatics by Author "Kell, Douglas B."

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  • Fast automatic registration of images using the phase of a complex wavelet transform: application to proteome gels 
    Woodward, Andrew M.; Rowland, Jem; Kell, Douglas B. (2004)
    Image registration describes the process of manipulating a distorted version of an image such that its pixels overlay the equivalent pixels in a clean, master or reference image. The need for it has assumed particular ...
  • Functional genomic hypothesis generation and experimentation by a robot scientist 
    Muggleton, S.; Whelan, Ken; Jones, F. M.; Reiser, P. G. K.; Kell, Douglas B.; Oliver, Stephen G.; Bryant, Christopher H.; King, Ross Donald (2004)
    The question of whether it is possible to automate the scientific process is of both great theoretical interest and increasing practical importance because, in many scientific areas, data are being generated much faster ...
  • Further developments towards a genome-scale metabolic model of yeast 
    Smallbone, Kieran; Kell, Douglas B.; Dunn, Warwick B.; Stanford, Natalie J.; Swainston, Neil; Fisher, Paul; Jameson, Daniel; Simeonidis, Evangelos; Dobson, Paul D.; Hull, Duncan; Lu, Chuan; Oliver, Stephen G.; Lanthaler, Karin; King, Ross Donald; Mendes, Pedro; Oshota, Olusegun; Pir, Pınar; Brown, Marie; Stevens, Robert D. (2011-06-06)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...
  • A general model of error-prone PCR 
    Pritchard, Leighton; Corne, D.; Kell, Douglas B.; Winson, Mike K.; Rowland, Jem (2005-06-21)
    In this paper, we generalise a previously-described model of the error-prone polymerase chain reaction (PCR) reaction to conditions of arbitrarily variable amplification efficiency and initial population size. Generalisation ...
  • Primary and secondary metabolism, and post-translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor 
    Hesketh, A. R.; Chandra, G.; Shaw, Adrian; Rowland, Jem; Kell, Douglas B.; Bibb, M. J.; Chater, K. F. (2002)
    The newly sequenced genome of Streptomyces coelicolor is estimated to encode 7825 theoretical proteins. We have mapped approximately 10% of the theoretical proteome experimentally using two-dimensional gel electrophoresis ...

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