Browsing Computational Biology and Bioinformatics by Author "Oliver, Stephen G."

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Browsing Computational Biology and Bioinformatics by Author "Oliver, Stephen G."

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  • Constraint-based optimisation tools for semi-automated refinement of genome-scale yeast metabolic models 
    Pir, Pinar; Dobson, Paul D.; Smallbone, Kieran; Mendes, Pedro; King, Ross Donald; Lu, Chuan; Oliver, Stephen G.; Clare, Amanda (2010-10)
    Background: Genome-scale metabolic network models have been widely used for analysing the cellular behaviour of organisms both qualitatively and quantitatively. An iterative semi-automated procedure for model validation ...
  • Functional genomic hypothesis generation and experimentation by a robot scientist 
    Muggleton, S.; Whelan, Ken; Jones, F. M.; Reiser, P. G. K.; Kell, Douglas B.; Oliver, Stephen G.; Bryant, Christopher H.; King, Ross Donald (2004)
    The question of whether it is possible to automate the scientific process is of both great theoretical interest and increasing practical importance because, in many scientific areas, data are being generated much faster ...
  • Further developments towards a genome-scale metabolic model of yeast 
    Smallbone, Kieran; Kell, Douglas B.; Dunn, Warwick B.; Stanford, Natalie J.; Swainston, Neil; Fisher, Paul; Jameson, Daniel; Simeonidis, Evangelos; Dobson, Paul D.; Hull, Duncan; Lu, Chuan; Oliver, Stephen G.; Lanthaler, Karin; King, Ross Donald; Mendes, Pedro; Oshota, Olusegun; Pir, Pınar; Brown, Marie; Stevens, Robert D. (2011-06-06)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...

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