Browsing Bioinformatics and Computational Biology Group by Author "Oliver, Stephen G."

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  • Pir, Pinar; Dobson, Paul D.; Smallbone, Kieran; Mendes, Pedro; King, Ross Donald; Lu, Chuan; Oliver, Stephen G.; Clare, Amanda (2010-10)
    Background: Genome-scale metabolic network models have been widely used for analysing the cellular behaviour of organisms both qualitatively and quantitatively. An iterative semi-automated procedure for model validation ...
  • King, Ross Donald; Whelan, Kenneth Edward; Jones, Ffion M.; Reiser, Philip G. K.; Bryant, Christopher H.; Muggleton, Stephen H.; Kell, Douglas B.; Oliver, Stephen G. (2004-01-15)
    The question of whether it is possible to automate the scientific process is of both great theoretical interest and increasing practical importance because, in many scientific areas, data are being generated much faster ...
  • Jones, Andrew R.; Miller, Michael; Aebersold, Ruedi; Apweiler, Rolf; Ball, Catherine A.; Brazma, Alvis; DeGreef, James; Hardy, Nigel; Hermjakob, Henning; Hubbard, Simon J.; Hussey, Peter; Igra, Mark; Jenkins, Helen; Julian Jr, Randall K.; Laursen, Kent; Oliver, Stephen G.; Paton, Norman W.; Sansone, Susanna-Assunta; Sarkans, Ugis; Stoeckert Jr, Christian J.; Taylor, Chris F.; Whetzel, Patricia L.; White, Joseph A.; Spellman, Paul; Pizarro, Angel (2007-10-05)
    The Functional Genomics Experiment data model (FuGE) has been developed to facilitate convergence of data standards for high-throughput, comprehensive analyses in biology. FuGE models the components of an experimental ...
  • Dobson, Paul D.; Smallbone, Kieran; Jameson, Daniel; Simeonidis, Evangelos; Lanthaler, Karin; Pir, Pınar; Lu, Chuan; Swainston, Neil; Dunn, Warwick B.; Fisher, Paul; Hull, Duncan; Brown, Marie; Oshota, Olusegun; Stanford, Natalie J.; Kell, Douglas B.; King, Ross Donald; Oliver, Stephen G.; Stevens, Robert D.; Mendes, Pedro (2010-10-28)
    Background. To date, several genome-scale network reconstructions have been used to describe the metabolism of the yeast Saccharomyces cerevisiae, each differing in scope and content. The recent community-driven reconstruction, ...
  • Byrne, Emma Louise; Liakata, Maria; Whelan, Kenneth Edward; Oliver, Stephen G.; Rowland, Jeremy John; Aubrey, Wayne; Soldatova, Larisa Nikolaevna; Sparkes, Andrew Charles; Young, Michael; Markham, Magdalena; Clare, Amanda Janet; Pir, Pinar; King, Ross Donald (2009-08-21)
    In their 19 June letter ('Machines fall short of revolutionary science,' p. 1515), P. W. Anderson and E. Abrahams, commenting on our work on the automation of science, state that we are 'seriously mistaken about the nature ...
  • Spasić, Irena; Dunn, Warwick B.; Velarde, Giles; Tseng, Andy; Jenkins, Helen; Hardy, Nigel; Oliver, Stephen G.; Kell, Douglas B. (2006-06-05)
    Background The genome sequencing projects have shown our limited knowledge regarding gene function, e.g. S. cerevisiae has 5–6,000 genes of which nearly 1,000 have an uncertain function. Their gross influence on the behaviour ...
  • King, Ross Donald; Liakata, Maria; Lu, Chuan; Oliver, Stephen G.; Soldatova, Larisa Nikolaevna (2011-10-07)
    The reuse of scientific knowledge obtained from one investigation in another investigation is basic to the advance of science. Scientific investigations should therefore be recorded in ways that promote the reuse of the ...

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