Show simple item record Luis A. J. en_US Paul en_US Amanda J. en_US Helen J. en_US Elena en_US 2009-05-21T12:53:36Z 2009-05-21T12:53:36Z 2007-12-12 en_US
dc.identifier en_US
dc.identifier.citation Mur , L A J , Kenton , P , Lloyd , A J , Ougham , H J & Prats , E 2007 , ' The hypersensitive response; the centenary is upon us but how much do we know? ' Journal of Experimental Botany , vol 59 , no. 3 , pp. 501-520 . , 10.1093/jxb/erm239 en_US
dc.identifier.other PURE: 103119 en_US
dc.identifier.other dspace: 2160/2336 en_US
dc.description.abstract With the centenary of the first descriptions of ‘hypersensitiveness’ following pathogenic challenge upon us, it is appropriate to assess our current understanding of the hypersensitive response (HR) form of cell death. In recent decades our understanding of the initiation, associated signalling, and some important proteolytic events linked to the HR has dramatically increased. Genetic approaches are increasingly elucidating the function of the HR initiating resistance genes and there have been extensive analyses of death-associated signals, calcium, reactive oxygen species (ROS), nitric oxide, salicylic acid, and now sphingolipids. At the same time, attempts to draw parallels between mammalian apoptosis and the HR have been largely unsuccessful and it may be better to consider the HR to be a distinctive form of plant cell death. We will consider if the HR form of cell death may occur through metabolic dysfunction in which malfunctioning organelles may play a major role. This review will highlight that although our knowledge of parts of the HR is excellent, a comprehensive molecular model is still to be attained. en_US
dc.format.extent 20 en_US
dc.relation.ispartof Journal of Experimental Botany en_US
dc.subject pathogen en_US
dc.subject hypersensitive response en_US
dc.subject programmed cell death en_US
dc.subject resistance en_US
dc.title The hypersensitive response; the centenary is upon us but how much do we know? en_US
dc.contributor.pbl Institute of Biological, Environmental and Rural Sciences en_US

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