Show simple item record Kato, Atsushi Kato, Noriko Miyauchi, Saori Minoshima, Yuka Adachi, Isao Ikeda, Kyoko Asano, Naoki Watson, Alison A. Nash, Robert J. 2009-05-21T13:02:11Z 2009-05-21T13:02:11Z 2008-03
dc.identifier.citation Kato , A , Kato , N , Miyauchi , S , Minoshima , Y , Adachi , I , Ikeda , K , Asano , N , Watson , A A & Nash , R J 2008 , ' Iminosugars from Baphia mitida Lodd ' Phytochemistry , vol 69 , no. 5 , pp. 1261-1265 . DOI: 10.1016/j.phytochem.2007.11.018 en
dc.identifier.issn 1873-3700
dc.identifier.other PURE: 103153
dc.identifier.other PURE UUID: 3139a0bc-972a-468b-879d-7005c143c81e
dc.identifier.other dspace: 2160/2337
dc.identifier.other DSpace_20121128.csv: row: 1707
dc.identifier.other IBERS: 0000017127
dc.identifier.other Ibers_20121112_1204.csv: row: 203
dc.identifier.other Scopus: 39649089378
dc.identifier.other PubMed: 18191969
dc.description Kato, A., Kato, N., Miyauchi, S., Minoshima, Y., Adachi, I., Ikeda, K., Asano, N., Watson, A. A., Nash, R. J. (2008). Iminosugars from Baphia mitida Lodd.  Phytochemistry, 69, 1261-1265. Sponsorship: Ministry of Education, Culture, Sports, Science and Technology, Grant-in-Aid for Young Scientists, 18790086 and Cooperative Research Center of Life Science . On file IMPF: 02.95 RONO: 00 en
dc.description.abstract Chromatographic separation of the 50% aqueous EtOH extract of the leaves of the African medicinal tree Baphia nitida resulted in isolation of 10 iminosugars. The plant contained 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine (DMDP) as a major alkaloid. The structure of a new alkaloid was also elucidated by spectroscopic methods as the 1-O-β-d-fructofuranoside of DMDP, and this plant produced 3-O-β-d-glucopyranosyl-DMDP as well. DMDP is a potent inhibitor of β-glucosidase and β-galactosidase, whereas the other two derivatives lowered inhibition toward both of these enzymes and improved inhibitory activities toward rice α-glucosidase and rat intestinal maltase. en
dc.format.extent 5 en
dc.language.iso eng
dc.relation.ispartof Phytochemistry en
dc.rights en
dc.title Iminosugars from Baphia mitida Lodd en
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article en
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en

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