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dc.contributor.author Kato, Atsushi
dc.contributor.author Kato, Noriko
dc.contributor.author Miyauchi, Saori
dc.contributor.author Minoshima, Yuka
dc.contributor.author Adachi, Isao
dc.contributor.author Ikeda, Kyoko
dc.contributor.author Asano, Naoki
dc.contributor.author Watson, Alison A.
dc.contributor.author Nash, Robert J.
dc.date.accessioned 2009-05-21T13:02:11Z
dc.date.available 2009-05-21T13:02:11Z
dc.date.issued 2008-03
dc.identifier.citation Kato , A , Kato , N , Miyauchi , S , Minoshima , Y , Adachi , I , Ikeda , K , Asano , N , Watson , A A & Nash , R J 2008 , ' Iminosugars from Baphia mitida Lodd ' Phytochemistry , vol 69 , no. 5 , pp. 1261-1265 . , 10.1016/j.phytochem.2007.11.018 en
dc.identifier.other PURE: 103153
dc.identifier.other dspace: 2160/2337
dc.identifier.uri http://hdl.handle.net/2160/2337
dc.description Kato, A., Kato, N., Miyauchi, S., Minoshima, Y., Adachi, I., Ikeda, K., Asano, N., Watson, A. A., Nash, R. J. (2008). Iminosugars from Baphia mitida Lodd.  Phytochemistry, 69, 1261-1265. Sponsorship: Ministry of Education, Culture, Sports, Science and Technology, Grant-in-Aid for Young Scientists, 18790086 and Cooperative Research Center of Life Science . On file IMPF: 02.95 RONO: 00 en
dc.description.abstract Chromatographic separation of the 50% aqueous EtOH extract of the leaves of the African medicinal tree Baphia nitida resulted in isolation of 10 iminosugars. The plant contained 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine (DMDP) as a major alkaloid. The structure of a new alkaloid was also elucidated by spectroscopic methods as the 1-O-β-d-fructofuranoside of DMDP, and this plant produced 3-O-β-d-glucopyranosyl-DMDP as well. DMDP is a potent inhibitor of β-glucosidase and β-galactosidase, whereas the other two derivatives lowered inhibition toward both of these enzymes and improved inhibitory activities toward rice α-glucosidase and rat intestinal maltase. en
dc.format.extent 5 en
dc.language.iso eng
dc.relation.ispartof Phytochemistry en
dc.title Iminosugars from Baphia mitida Lodd en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.identifier.doi http://dx.doi.org/10.1016/j.phytochem.2007.11.018
dc.contributor.institution Aberystwyth University en
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en


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