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dc.contributor.author Atsushi en_US
dc.contributor.author Noriko en_US
dc.contributor.author Saori en_US
dc.contributor.author Yuka en_US
dc.contributor.author Isao en_US
dc.contributor.author Kyoko en_US
dc.contributor.author Naoki en_US
dc.contributor.author Alison A. en_US
dc.contributor.author Robert J. en_US
dc.date.accessioned 2009-05-21T13:02:11Z
dc.date.available 2009-05-21T13:02:11Z
dc.date.issued 2008-03 en_US
dc.identifier http://dx.doi.org/10.1016/j.phytochem.2007.11.018 en_US
dc.identifier.citation Kato , A , Kato , N , Miyauchi , S , Minoshima , Y , Adachi , I , Ikeda , K , Asano , N , Watson , A A & Nash , R J 2008 , ' Iminosugars from Baphia mitida Lodd ' Phytochemistry , vol 69 , no. 5 , pp. 1261-1265 . , 10.1016/j.phytochem.2007.11.018 en_US
dc.identifier.other PURE: 103153 en_US
dc.identifier.other dspace: 2160/2337 en_US
dc.identifier.uri http://hdl.handle.net/2160/2337
dc.description.abstract Chromatographic separation of the 50% aqueous EtOH extract of the leaves of the African medicinal tree Baphia nitida resulted in isolation of 10 iminosugars. The plant contained 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine (DMDP) as a major alkaloid. The structure of a new alkaloid was also elucidated by spectroscopic methods as the 1-O-β-d-fructofuranoside of DMDP, and this plant produced 3-O-β-d-glucopyranosyl-DMDP as well. DMDP is a potent inhibitor of β-glucosidase and β-galactosidase, whereas the other two derivatives lowered inhibition toward both of these enzymes and improved inhibitory activities toward rice α-glucosidase and rat intestinal maltase. en_US
dc.format.extent 5 en_US
dc.relation.ispartof Phytochemistry en_US
dc.title Iminosugars from Baphia mitida Lodd en_US
dc.contributor.pbl Aberystwyth University en_US
dc.contributor.pbl Institute of Biological, Environmental and Rural Sciences en_US


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