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dc.contributor.author Nash, Robert J.
dc.contributor.author Asano, Naoki
dc.contributor.author Winters, Ana L.
dc.contributor.author Yu, C. Y.
dc.contributor.author Fleet, George W. J.
dc.contributor.author Butters, T. D.
dc.contributor.author Ikeda, Kyoko
dc.contributor.author Dwek, R. A.
dc.contributor.author Wormald, M. R.
dc.contributor.author Wang, M. X.
dc.date.accessioned 2009-09-24T11:11:33Z
dc.date.available 2009-09-24T11:11:33Z
dc.date.issued 2004-07-29
dc.identifier.citation Nash , R J , Asano , N , Winters , A L , Yu , C Y , Fleet , G W J , Butters , T D , Ikeda , K , Dwek , R A , Wormald , M R & Wang , M X 2004 , ' Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP ' Chemical Communications , pp. 1936-1937 . , 10.1039/b406035k en
dc.identifier.issn 1364-548X
dc.identifier.other PURE: 121421
dc.identifier.other dspace: 2160/3071
dc.identifier.uri http://hdl.handle.net/2160/3071
dc.description Yu, C. Y., Asano, N., Ikeda, K., Wang, M. X., Butters, T. D., Wormald, M. R., Dwek, R. A., Winters, A. L., Nash, R. J., Fleet, G. W. J. (2004). Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP. Chemical Communications, 17, 1936-1937. Sponsorship: Royal Society of London/Chinese Academy of Sciences en
dc.description.abstract L-DMDP, prepared from D-gulonolactone, is a highly specific inhibitor of a number of plant and mammalian -glucosidases [between 2 and 4 orders of magnitude more potent than the enantiomeric natural product DMDP] but is not an inhibitor of bacterial and yeast -glucosidases. Additionally N-butyl-DMDP is a potent inhibitor of ceramide-specific glucosyltransferase but N-butyl-L-DMDP shows no inhibition. en
dc.format.extent 2 en
dc.language.iso eng
dc.relation.ispartof Chemical Communications en
dc.title Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.identifier.doi http://dx.doi.org/10.1039/b406035k
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en


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