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dc.contributor.author Palestis, Brian G.
dc.contributor.author Burt, Austin
dc.contributor.author Jones, R. Neil
dc.contributor.author Trivers, Robert
dc.date.accessioned 2009-10-16T11:20:26Z
dc.date.available 2009-10-16T11:20:26Z
dc.date.issued 2004-02-07
dc.identifier.citation Palestis , B G , Burt , A , Jones , R N & Trivers , R 2004 , ' B chromosomes are more frequent in mammals with acrocentric karyotypes: support for the theory of centromeric drive ' Proceedings of the Royal Society B: Biological Sciences , vol 271 , no. S3 , pp. S22-S24 . , 10.1098/rsbl.2003.0084 en
dc.identifier.issn 0962-8452
dc.identifier.other PURE: 124001
dc.identifier.other dspace: 2160/3231
dc.identifier.uri http://hdl.handle.net/2160/3231
dc.description Palestis, B. G., Burt, A., Jones, R. N., Trivers, R. (2004). B chromosomes are more frequent in mammals with acrocentric karyotypes: support for the theory of centromeric drive.   Proceedings of the Royal Society of London Series B-Biological Sciences, 271, (Supplement 3), S22-S24. Sponsorship: Megerle family and the Biosocial Research Foundation en
dc.description.abstract The chromosomes of mammals tend to be either mostly acrocentric (having one long arm) or mostly bi–armed, with few species having intermediate karyotypes. The theory of centromeric drive suggests that this observation reflects a bias during female meiosis, favouring either more centromeres or fewer, and that the direction of this bias changes frequently over evolutionary time. B chromosomes are selfish genetic elements found in some individuals within some species. B chromosomes are often harmful, but persist because they drive (i.e. they are transmitted more frequently than expected). We predicted that species with mainly acrocentric chromosomes would be more likely to harbour B chromosomes than those with mainly bi–armed chromosomes, because female meiosis would favour more centromeres over fewer in species with one–armed chromosomes. Our results show that B chromosomes are indeed more common in species with acrocentric chromosomes, across all mammals, among rodents, among non–rodents and in a test of independent taxonomic contrasts. These results provide independent evidence supporting the theory of centromeric drive and also help to explain the distribution of selfish DNA across species. In addition, we demonstrate an association between the shape of the B chromosomes and the shape of the typical (‘A’) chromosomes. en
dc.language.iso eng
dc.relation.ispartof Proceedings of the Royal Society B: Biological Sciences en
dc.subject B chromosomes en
dc.subject centromeric drive en
dc.subject karyotype en
dc.subject meiotic drive en
dc.subject selfish DNA en
dc.title B chromosomes are more frequent in mammals with acrocentric karyotypes: support for the theory of centromeric drive en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.identifier.doi http://dx.doi.org/10.1098/rsbl.2003.0084
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en


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