Unfolding large-scale maps

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dc.contributor.author Jenkins, Glyn M.
dc.date.accessioned 2009-11-03T12:10:51Z
dc.date.available 2009-11-03T12:10:51Z
dc.date.issued 2003
dc.identifier.citation Jenkins , G M 2003 , ' Unfolding large-scale maps ' Genome , vol 46 , no. 6 , pp. 947-952 . , 10.1139/g03-113 en
dc.identifier.issn 0831-2796
dc.identifier.other PURE: 139480
dc.identifier.other dspace: 2160/3408
dc.identifier.uri http://hdl.handle.net/2160/3408
dc.description Jenkins, G. (2003). Unfolding large-scale maps.   Genome, 46, (6), 947-952. en
dc.description.abstract This is an account of the development and use of genetic maps, from humble beginnings at the hands of Thomas Hunt Morgan, to the sophistication of genome sequencing. The review charters the emergence of molecular marker maps exploiting DNA polymorphism, the renaissance of cytogenetics through the use of fluorescence in situ hybridisation, and the discovery and isolation of genes by map-based cloning. The historical significance of sequencing of DNA prefaces a section describing the sequencing of genomes, the ascendancy of particular model organisms, and the utility and limitations of comparative genomic and functional genomic approaches to further our understanding of the control of biological processes. Emphasis is given throughout the treatise as to how the structure and biological behaviour of the DNA molecule underpin the technological development and biological applications of maps. en
dc.format.extent 6 en
dc.language.iso eng
dc.relation.ispartof Genome en
dc.title Unfolding large-scale maps en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.identifier.doi http://dx.doi.org/10.1139/g03-113
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en


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