Abstract:
The genome verified C. elegans free-living nematode model is a new tool for investigating gene expression in human and animal nematode parasites. There is limited information on designating glutathione S-transferase (GST) to specific classes in lower invertebrates such as nematodes. Following cloning, amino acid sequence alignment, recombinant expression and Western blotting we provide evidence of a new GST class in nematodes or lower invertebrates.
Description:
Campbell, A. M., Teesdale-Spittle, P. H., Barrett, J., Liebau, E., Jefferies, J. R., Brophy, P. M. (2001). A common class of nematode gluthione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans. Comparative Biochemistry and Physiology B - Biochemistry and Molecular Biology, 128, (4), 701-708. Sponsorship: UNDP/WORLD BANK/WHO Special Programme for Tropical Disease Research (TDR 96/011) / BBSRC