Show simple item record Lamb, David Christopher Kelly, Steven Lewis Kelly, Diane Elizabeth 2009-11-25T16:14:42Z 2009-11-25T16:14:42Z 2001
dc.identifier.citation Lamb , D C , Kelly , S L & Kelly , D E 2001 , ' Genome-wide generation of yeast gene deletion strains ' Comparative and Functional Genomics , vol 2 , no. 4 , pp. 236-242 . DOI: 10.1002/cfg.95 en
dc.identifier.issn 1532-6268
dc.identifier.other PURE: 130384
dc.identifier.other PURE UUID: 4972044c-9fcb-4066-936d-7feb73c207a5
dc.identifier.other dspace: 2160/3635
dc.identifier.other DSpace_20121128.csv: row: 2801
dc.identifier.other Scopus: 0034861074
dc.identifier.other PubMed: 18628917
dc.identifier.other PubMedCentral: PMC2447215
dc.description Kelly, D. E., Lamb, D. C., Kelly, S. L. (2001). Genome-wide generation of yeast gene deletion strains. Comparative and Functional Genomics, 2, (4), 236-242. Sponsorship: EU/BBSRC/MRC en
dc.description.abstract In the year 2001 a collection of yeast strains will be completed that are deleted in the 6000 open reading frames selected as putative genes by the initial bioinformatic analysis of the Saccharomyces cerevisiae genome. The collection was produced by the transatlantic yeast gene deletion project, a collaboration involving researchers in the USA, Canada and Europe. The European effort was part of EUROFAN (European Functional Analysis Network) where some of the strains could feed into various functional analysis nodes dealing with specific areas of cell biology. With approximately 40% of human genes involved in heritable disease having a homologue in yeast and with the use of yeast in various drug discovery strategies, not least due to the dramatic increase in fungal infections, these strains will be valuable in trans-genomic studies and in specialised interest studies in individual laboratories. A detailed analysis of the project by the consortium is in preparation, here we discuss the yeast strains, reported findings and approaches to using this resource. en
dc.format.extent 7 en
dc.language.iso eng
dc.relation.ispartof Comparative and Functional Genomics en
dc.rights en
dc.title Genome-wide generation of yeast gene deletion strains en
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article en
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en

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