Show simple item record Douglas B. en_US Leighton en_US 2010-01-07T10:28:36Z 2010-01-07T10:28:36Z 2002-08-05 en_US
dc.identifier en_US
dc.identifier.citation Kell , D B & Pritchard , L 2002 , ' Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis ' European Journal of Biochemistry , vol 269 , no. 16 , pp. 3894-3904 . , 10.1046/j.1432-1033.2002.03055.x en_US
dc.identifier.other PURE: 134695 en_US
dc.identifier.other dspace: 2160/3945 en_US
dc.description.abstract We used parameter scanning to emulate changes to the limiting rate for steps in a fitted model of glucose-derepressed yeast glycolysis. Three flux-control regimes were observed, two of which were under the dominant control of hexose transport, in accordance with various experimental studies and other model predictions. A third control regime in which phosphofructokinase exerted dominant glycolytic flux control was also found, but it appeared to be physiologically unreachable by this model, and all realistically obtainable flux control regimes featured hexose transport as a step involving high flux control. en_US
dc.format.extent 11 en_US
dc.relation.ispartof European Journal of Biochemistry en_US
dc.title Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis en_US
dc.contributor.pbl Aberystwyth University en_US
dc.contributor.pbl Institute of Biological, Environmental and Rural Sciences en_US

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