Browsing Gwyddorau Biolegol, Amgylcheddol a Gwledig / Biological, Environmental & Rural Sciences by Author "Asano, Naoki"

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Browsing Gwyddorau Biolegol, Amgylcheddol a Gwledig / Biological, Environmental & Rural Sciences by Author "Asano, Naoki"

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  • Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae) 
    Kato, Atsushi; Ikeda, Kyoko; Watson, Alison A.; Haraguchi, M.; Minami, Y.; Asano, Naoki; Nash, Robert J.; Molyneux, R. J.; Gorniak, S. L. (2003-07-11)
    Natural intoxication of livestock by the ingestion of Ipomoea carnea (Convolvulaceae) sometimes occurs in tropical regions of the world. Polyhydroxylated alkaloids were isolated from the leaves, flowers, and seeds of the ...
  • Dihydroxynortropane alkaloids from calystegine-producing plants 
    Arisawa, M.; Hoke, D.; al, et; Drager, B.; Asano, Naoki; Yokoyama, K.; Ikeda, Kyoko; Sakurai, M.; Kizu, Haruhisa; Kato, Atsushi; Watson, Alison A. (2001-07)
    Three dihydroxynortropanes, 2α,7β-dihydroxynortropane, 2α,3β-dihydroxynortropane, and 3α,7β-dihydroxynortropane, were isolated from calystegine-producing plants in the families Convolvulaceae and Solanaceae. 2α,7β-Dihydr ...
  • Iminosugars from Baphia mitida Lodd 
    Kato, Atsushi; Kato, Noriko; Miyauchi, Saori; Minoshima, Yuka; Adachi, Isao; Ikeda, Kyoko; Asano, Naoki; Watson, Alison A.; Nash, Robert J. (2008-03)
    Chromatographic separation of the 50% aqueous EtOH extract of the leaves of the African medicinal tree Baphia nitida resulted in isolation of 10 iminosugars. The plant contained 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine ...
  • Inhibitory effects of Zingiber officinale roscoe derived components on aldose reductase activity in vitro and in vivo 
    Kato, Atsushi; Nash, Robert J.; Asano, Naoki; Okamoto, T.; Kizu, Haruhisa; Higuchi, Y.; Adachi, Isao; Goto, H.; Hollinshead, Jackie (2006-08-05)
    Ginger (Zingiber officinale Roscoe) continues to be used as an important cooking spice and herbal medicine around the world. Scientific research has gradually verified the antidiabetic effects of ginger. Especially gingerols, ...
  • Looking glass inhibitors: L-DMDP, a more potent and specific inhibitor of alpha-glucosidases than the enantiomeric natural product DMDP 
    Nash, Robert J.; Asano, Naoki; Winters, Ana L.; Yu, C. Y.; Fleet, George W. J.; Butters, T. D.; Ikeda, Kyoko; Dwek, R. A.; Wormald, M. R.; Wang, M. X. (2004-07-29)
    L-DMDP, prepared from D-gulonolactone, is a highly specific inhibitor of a number of plant and mammalian -glucosidases [between 2 and 4 orders of magnitude more potent than the enantiomeric natural product DMDP] but is not ...
  • Novel alpha-L-fucosidase inhibitors from the bark of Angylocalyx pynaertii (Leguminosae) 
    Yasuda, Kayo; Fan, J. -. Q.; Kizu, Haruhisa; Molyneux, R. J.; Nash, Robert J.; Kato, Atsushi; Asano, Naoki; Fleet, George W. J. (2001-01)
    The extract of bark of Angylocalyx pynaertii (Leguminosae) was found to potently inhibit mammalian α- l-fucosidases. A thorough examination of the extract resulted in the discovery of 15 polyhydroxylated alkaloids, including ...
  • Polyhydroxylated alkaloids isolated from mulberry trees (Morus alba L.) and silkworms (Bombyx mori L.) 
    Kato, Atsushi; Lee, Heui S.; Kizu, Haruhisa; Kameda, Yukihiko; Ikeda, Kyoko; Nash, Robert J.; Yasuda, Kayo; Ryu, Kang S.; Asano, Naoki; Yamashita, Toru (2001-08-16)
    New polyhydroxylated alkaloids, (2R,3R,4R)-2-hydroxymethyl-3,4-dihydroxypyrrolidine-N-propionamide from the root bark of Morus alba L., and 4-O-α-d-galactopyranosyl-calystegine B2 and 3β,6β-dihydroxynortropane from the ...
  • Polyhydroxylated alkaloids - natural occurrence and therapeutic applications 
    Asano, Naoki; Fleet, George W. J.; Watson, Alison A.; Molyneux, Russell J.; Nash, Robert J. (2001)
    Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study ...
  • Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase 
    Nash, Robert J.; Minami, Y.; Nasu, N.; Asano, Naoki; Kato, Atsushi; Watson, Alison A.; Takebayashi, K.; Adachi, Isao; Sanae, F. (2008)
    Flavonoids are ubiquitous components in vegetables, fruits, tea, and wine. Therefore, they are often consumed in large quantities in our daily diet. Several flavonoids have been shown to have potential as antidiabetic ...

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