Browsing Gwyddorau Biolegol, Amgylcheddol a Gwledig / Biological, Environmental & Rural Sciences by Author "Aso, Hisashi"

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  • Nagai, Yasuhiro; Aso, Hisashi; Ogasawara, Hidiki; Tanaka, Sachi; Taketa, Yoshikazu; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, M. T.; Kitazawa, Haruki; Yamaguchi, Takahiro (2008-11-01)
    Stem/Progenitor cells in the postnatal pituitary gland are embedded in a marginal cell layer around Rathke’s pouch. However, the nature and behavior of anterior pituitary progenitor cells remain unclear. We established ...
  • Nagai, Yasuhiro; Aso, Hisashi; Ogasawara, Hideki; Tanaka, Sachi; Taketa, Yoshikazu; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, Michael T.; Kitazawa, Haruki; Yamaguchi, Takahiro (2008-11-01)
    Stem/Progenitor cells in the postnatal pituitary gland are embedded in a marginal cell layer around Rathke’s pouch. However, the nature and behavior of anterior pituitary progenitor cells remain unclear. We established ...
  • Miyazawa, Kohtaro; Aso, Hisashi; Kanaya, Takashi; Kido, Taketomo; Minashima, Takeshi; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T.; Tahara, Koji; Yamasaki, Tadashi; Yamaguchi, Takahiro (2006-03)
    Membranous (M) cells of the follicle-associated epithelium (FAE) are believed to sample antigens from the gut lumen. However, the origin, differentiation mechanism, and cell death of M cells are still a matter of controversy. ...
  • Miyazawa, Kohtaro; Hondo, Tetsuya; Kanaya, Takashi; Tanaka, Sachi; Takakura, Ikuro; Itani, Wataru; Rose, Michael Terence; Kitazawa, Haruki; Yamaguchi, Takahiro; Aso, Hisashi (2010-01)
    Membranous epithelial cells (M cells) of the follicle-associated epithelium in Peyer's patches have a high capacity for transcytosis of several viruses and microorganisms. Here, we report that we have successfully established ...
  • Tahara, Koji; Aso, Hisashi; Yamasaki, Tadashi; Rose, Michael T.; Takasuga, Akiko; Sugimoto, Yoshikazu; Yamaguchi, Takahiro; Takano, Shoichi (2004-04)
    In order to isolate candidate genes involved in bovine adipocyte differentiation, we have constructed a subtraction library from a clonal bovine intra-muscular pre-adipocyte (BIP) cell line using the suppression subtractive ...
  • Sanosaka, Masato; Minashima, Takeshi; Suzuki, Keiichi; Watanabe, Kouichi; Ohwada, Shyuichi; Hagino, Akihiko; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2008-02)
    To understand the relationship between intramuscular adipogenesis in the pig and the supply fatty acids, we established a clonal porcine intramuscular preadipocyte (PIP) line from the marbling muscle tissue of female Duroc ...
  • Hondo, Tetsuya; Kanaya, Takashi; Takakura, Ikuro; Watanabe, Hitoshi; Takahashi, Yu; Nagasawa, Yuya; Terada, Shunsuke; Ohwada, Shyuichi; Watanabe, Kouichi; Kitazawa, Haruki; Rose, Michael Terence; Yamaguchi, Takahiro; Aso, Hisashi (2011-03-01)
    Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches have an important role in mucosal immune responses. A primary difficulty for investigations of bovine M cells is the lack of a specific ...
  • Kanaya, Takashi; Miyazawa, Kohtaro; Takakura, Ikuro; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, M. T.; McConochie, H. R.; Okano, Hideyuki; Yamaguchi, Takahiro; Aso, Hisashi (2008-08-01)
    M cells are a kind of intestinal epithelial cell in the follicle-associated epithelium of Peyer's patches. These cells can transport antigens and microorganisms into underlying lymphoid tissues. Despite the important role ...
  • Aso, Hisashi; Tamura, Keiji; Rose, M T; Tomioka, Yoshihisa; Mizugaki, Michinao; Ishida, Nakao (1999-04)
    The in vitro effect of C-AGP (pure alpha1-acid glycoprotein from the ascitic fluid of cancer patients) on NK cell cytotoxicity was tested using normal healthy human PBMC. C-AGP had no inhibitory effect on basal NK cell ...
  • Iwasaki, Shunsuke; Miyake, Masato; Watanabe, Hitoshi; Kitagawa, Eri; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael Terence; Aso, Hisashi (2013-02)
    Recent studies show that myostatin mRNA expression is found in some regions of the brain. However, the functional significance of this is currently unknown. We therefore investigated myostatin expression and function in ...
  • Sakamoto, Kazuhito; Komatsu, Tokushi; Kobayashi, Takuya; Rose, Michael T.; Aso, Hisashi; Hagino, Akihiko; Obara, Yoshiaki (2005-08)
    To study the effect of growth hormone (GH) on the functions of mammary epithelia, we examined the effect of GH on the synthesis and secretion of α-casein in a bovine mammary epithelial cell (BMEC) clonal line, which was ...
  • Miyazawa, Kohtaro; Aso, Hisashi; Honda, Masashi; Kido, Taketomo; Minashima, Takeshi; Kanaya, Takashi; Watanabe, Kouichi; Ohwada, Shyuichi; Rose, Michael T.; Yamaguchi, Takahiro (2006-08)
    Dendritic cells (DCs) are professional antigen presenting cells, which initiate primary immune responses and also play an important role in the generation of peripheral tolerance. There is no reliable method established ...
  • Miyazawa, Kohtaro; Kanaya, Takashi; Tanaka, Sachi; Takakura, Ikuro; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T.; Sakaguchi, Suehiro; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2007-03)
    The gastrointestinal tract is thought to be the main site of entry for the pathological isoform of the prion protein (PrPSc). Prion diseases are believed to result from a conformational change of the cellular prion protein ...
  • Rose, Michael T.; Aso, Hisashi; Yonekura, Sinishi; Komatsu, Tokushi; Hagino, Akihiko; Ozutsumi, Kyouhei; Obara, Yoshiaki (2002-08)
    The aim of the study was to establish in vitro a bovine mammary epithelial cell (MEC) clone, able to respond to mitogenic growth factors and to lactogenic hormones. Mammary tissue from a 200-d pregnant Holstein cow was ...
  • Yamasaki, Tadashi; Tahara, Koji; Takano, Shoichi; Inoue-Murayama, Miho; Rose, Michael T.; Minashima, Takeshi; Aso, Hisashi; Ito, Shin'ichi (2006-10)
    Plasma glutathione peroxidase (pGPx) is an anti-oxidative enzyme. Using the polymerase chain reaction subtraction method, we have previously identified pGPx as a large part of the genes that are expressed following adipocyte ...
  • Takakura, Ikuro; Miyazawa, Kohtaro; Kanaya, Takashi; Itani, Wataru; Watanabe, Kouichi; Ohwada, Shyuichi; Watanabe, Hitoshi; Hondo, Tetsuya; Rose, Michael T; Mori, Tsuyoshi; Sakaguchi, Suehiro; Nishida, Noriyuki; Katamine, Shigeru; Yamaguchi, Takahiro; Aso, Hisashi (2011-09)
    Transmissible spongiform encephalopathies are fatal neurodegenerative diseases. Infection by the oral route is assumed to be important, although its pathogenesis is not understood. Using prion protein (PrP) knockout mice, ...
  • Watanabe, Hitoshi; Akasaka, Daisuke; Ogasawara, Hideki; Sato, Kan; Miyake, Masato; Saito, Kazuki; Takahashi, Yu; Kanaya, Takashi; Takakura, Ikuro; Hondo, Tetsuya; Chao, Guozheng; Rose, Michael Terence; Ohwada, Shyuichi; Watanabe, Kouichi; Yamaguchi, Takahiro; Aso, Hisashi (2010-10-01)
    Serotonin is synthesized by two distinct tryptophan hydroxylases, one in the brain and one in the periphery. The latter is known to be unable to cross the blood-brain barrier. These two serotonin systems have apparently ...
  • Yonekura, S.; Tokutake, Y; Hirota, T.; Rose, Michael Terence; Katoh, Kazuo; Aso, Hisashi (2013-07)
    Leptin is thought to be not only a satiety factor but also a stimulator of angiogenesis. We examined leptin, PPARgamma2, and vascular endothelial growth factor (VEGF) expression in bovine intramuscular preadipocyte (BIP) ...
  • Hayashi, Shinichiro; Aso, Hisashi; Watanabe, Shinichiro; Nara, Hidetoshi; Rose, Michael T.; Ohwada, Shyuichi; Yamaguchi, Takahiro (2000-11)
    Various cytokines are thought to play a role in muscle regeneration, however, the interaction and mechanisms of action of these cytokines remains largely unknown. In this study, we investigated the role of HGF, IGF-I, and ...
  • Kanaya, Takashi; Aso, Hisashi; Miyazawa, Kohtaro; Kido, Taketomo; Minashima, Takeshi; Watanabe, Kouichi; Ohwada, Shyuichi; Kitazawa, Haruki; Rose, Michael T; Yamaguchi, Takahiro (2007-04)
    M cells play a central role in the initiation of mucosal immune responses. However, a primary source of difficulty for investigations of this is the lack of an available specific marker for bovine M cells. As M cells possess ...

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