High resolution melting (HRM) can detect and quantify the presence of 5-methylcytosine (5mC) in DNA samples, but the ability of HRM to diagnose other DNA modifications remains unexplored. The DNA bases N6-methyladenine and ...

High Resolution Melt analysis (HRM) is a closed-tube method of genotyping that does not require use of fluorescent probes, fragment fractionation or amplicon sequence information. Recent advancements in florescent-detection ...