Show simple item record Molatova, Z. Skoivanova, E. Macias, B. McEwan, N. R. Boezina, P. Marounek, Milan 2011-06-03T08:25:44Z 2011-06-03T08:25:44Z 2010-05-01
dc.identifier.citation Molatova , Z , Skoivanova , E , Macias , B , McEwan , N R , Boezina , P & Marounek , M 2010 , ' Susceptibility of Campylobacter jejuni to organic acids and monoacylglycerols ' Folia Microbiologica , vol 55 , no. 3 , pp. 215-220 . DOI: 10.1007/s12223-010-0031-8 en
dc.identifier.issn 1874-9356
dc.identifier.other PURE: 163242
dc.identifier.other PURE UUID: 72e68b1b-8035-4de6-9157-88f374d8dc50
dc.identifier.other dspace: 2160/6895
dc.identifier.other DSpace_20121128.csv: row: 4158
dc.identifier.other IBERS: 0000017386
dc.identifier.other Ibers_20121112_1204.csv: row: 938
dc.identifier.other RAD: 1796
dc.identifier.other RAD_Outputs_All_ID_Import_20121105.csv: row: 968
dc.identifier.other Scopus: 77953411188
dc.description Molatova, Z., Skrivanova, E., Macías, B., McEwan, N. R., Brezina, P., Marounek, M. (2010). Susceptibility of Campylobacter jejuni to organic acids and monoacylglycerols   Folia. Microbiologica, 55, (3), 215-220 IMPF: 00.97 RONO: 00 en
dc.description.abstract Organic acids can be used as feed supplements or for treatment of poultry carcasses in processing plants. The antimicrobial activity of nineteen organic acids and two monoacylglycerols in cultures of Campylobacter jejuni CCM 6214T (ATCC 33560) was determined using a SYBR Green-based real-time PCR assay. The IC50 was a concentration at which only 50 % of a bacteria specific DNA sequence was amplified. Caprylic, capric and lauric acids were the most efficient antimicrobials among the compounds tested (IC50 ≤ 0.1 mg/mL). In a weakly acidic environment (pH 5.5), the antimicrobial activity was more pronounced than at pH 6.5. At pH 5.5, oleic and fumaric acid also had clear antimicrobial activity, as did monocaprylin. The antimicrobial activity of acetic, butyric, stearic and succinic acid was low. In cells treated with fumaric acid, the potential of potassium and tetraphenylphosphonium ion-selective electrodes changed, indicating an increase in cytoplasmic and outer membrane permeability, respectively. No changes in membrane permeability were observed in cells treated with capric acid or monocaprin. Transmission electron microscopy revealed separation of the inner and outer membrane in cells treated with capric and fumaric acid, as well as cytoplasmic disorganization in cells exposed to capric acid. en
dc.format.extent 6 en
dc.language.iso eng
dc.relation.ispartof Folia Microbiologica en
dc.rights en
dc.title Susceptibility of Campylobacter jejuni to organic acids and monoacylglycerols en
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article en
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en

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