Fetal calcium homeostasis  


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dc.contributor.author Care, A. D.
dc.date.accessioned 2011-06-06T14:27:43Z
dc.date.available 2011-06-06T14:27:43Z
dc.date.issued 1997-01
dc.identifier.citation Care , A D 1997 , ' Fetal calcium homeostasis   ' Equine Veterinary Journal , vol 29 , no. S24 , pp. 59-61 . en
dc.identifier.other PURE: 164815
dc.identifier.other dspace: 2160/6942
dc.identifier.uri http://hdl.handle.net/2160/6942
dc.identifier.uri http://www.ncbi.nlm.nih.gov/pubmed/9355803 en
dc.description Care, A. D. (2010). Fetal calcium homeostasis.   Equine Veterinary Journal, 29, (S24), 59-61. en
dc.description.abstract The mammalian fetus is maintained hypercalcaemic relative to its mother primarily by the action of a placental calcium pump located in the basal plasma membrane of the trophoblast. It is suggested that the activity of this pump is stimulated by a mid-molecular fragment of parathyroid hormone-related protein [PTHrP(38-94NH2)], produced in the placenta (and also in the parathyroid glands of fetal lambs and calves) as a result of post translational processing. In the sheep, calcitriol is an important determinant of fetal calcium homeostasis and it, too, stimulates the transport of calcium across the placenta. Fetal bone resorption is under the control of calcitriol, parathyroid hormone (PTH) and PTHrP. This resorption is modulated by the inhibitory effect of calcitonin. PTHrP also plays an important role in the regulation of endochondral ossification and chondrocyte maturation. en
dc.format.extent 3 en
dc.language.iso eng
dc.relation.ispartof Equine Veterinary Journal en
dc.title Fetal calcium homeostasis   en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.contributor.institution Aberystwyth University en
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en

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