Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization

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dc.contributor.author Zhang, Wei
dc.contributor.author Sato, Kasumi
dc.contributor.author Kato, Atsushi
dc.contributor.author Jia, Yue-mei
dc.contributor.author Hu, Xiang-guo
dc.contributor.author Wilson, Francis X.
dc.contributor.author Van Well, Renate
dc.contributor.author Horne, Graeme
dc.contributor.author Fleet, George W. J.
dc.contributor.author Nash, Robert J.
dc.contributor.author Yu, Chu-yi
dc.date.accessioned 2011-10-31T12:07:33Z
dc.date.available 2011-10-31T12:07:33Z
dc.date.issued 2011-08-19
dc.identifier.citation Zhang , W , Sato , K , Kato , A , Jia , Y , Hu , X , Wilson , F X , Van Well , R , Horne , G , Fleet , G W J , Nash , R J & Yu , C 2011 , ' Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization ' Organic Letters , vol 13 , no. 16 , pp. 4414-4417 . en
dc.identifier.issn 1523-7052
dc.identifier.other PURE: 172525
dc.identifier.other dspace: 2160/7642
dc.identifier.uri http://hdl.handle.net/2160/7642
dc.description Zhang, W., Sato, K., Kato, A., Jia, Y-M., Hu, X-G., Wilson, F. X., van Well, R., Horne, G., Fleet, G. W. J., Nash, R. J., Yu, C-Y. (2011). Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization. Organic Letters, 13 (16), 4414-4417. en
dc.description.abstract Total synthesis of the proposed structure of (-)-hyacinthacine C(5) and its epimers at C6 and C7 is described. A key step of the synthesis was the construction of the bicyclic pyrrolizidine system by means of a nucleophilic addition of a dithiane to a cyclic nitrone followed by a Cope House cyclization. en
dc.format.extent 4 en
dc.language.iso eng
dc.relation.ispartof Organic Letters en
dc.title Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization en
dc.type Text en
dc.type.publicationtype Article (Journal) en
dc.identifier.doi http://dx.doi.org/10.1021/ol201749c
dc.contributor.institution Institute of Biological, Environmental and Rural Sciences en
dc.description.status Peer reviewed en


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